What is the standard dosage of naloxone for treating an opioid overdose?

The standard dosage of naloxone for treating an opioid overdose is typically in the range of 0.4 to 2 mg, which can be repeated as needed, depending on the patient's response. Naloxone is an opioid antagonist and works by binding to opioid receptors, reversing the effects of opioid overdose such as respiratory depression and sedation.

The initial dosing is effective in quickly restoring respiratory function and consciousness in individuals who have experienced an overdose. The flexibility to repeat the dose is crucial, as the duration of action of opioid agonists can exceed that of naloxone. Therefore, if symptoms of overdose persist, further doses may be required, and this can be repeated every 2-3 minutes if the desired response is not observed.

It's essential to understand that other dosing options provided do not align with the standard guidelines for naloxone administration. Those dosages might either be too low or inappropriate for the emergency treatment of opioid overdose. Therefore, the correct choice reflects current clinical practices and guidelines, reinforcing the importance of proper naloxone administration in emergency settings.